||FOR RESEARCH USE ONLY (RUO).
||EAAT2 Antibody Positve Control-protein if for use in research applications.
||Store at-20°C for long term storage. Avoid freeze-thaw cycles.
| Post Translational Modifications || Glycosylated. Palmitoylation at Cys-38 is not required for correct subcellular localization, but is important for glutamate uptake activity. |
| Function || Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport.this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate. |
| Protein Name || Excitatory Amino Acid Transporter 2Glutamate/Aspartate Transporter IiSodium-Dependent Glutamate/Aspartate Transporter 2Solute Carrier Family 1 Member 2 |
| Database Links || Reactome: R-HSA-210455Reactome: R-HSA-210500Reactome: R-HSA-425393 |
| Cellular Localisation || Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names || Anti-Excitatory Amino Acid Transporter 2 antibodyAnti-Glutamate/Aspartate Transporter Ii antibodyAnti-Sodium-Dependent Glutamate/Aspartate Transporter 2 antibodyAnti-Solute Carrier Family 1 Member 2 antibodyAnti-SLC1A2 antibodyAnti-EAAT2 antibodyAnti-GLT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance