EAAT2 Antibody Positve Control protein (STJ505158)


Current Stock:
Applications: WB
Short Description: EAAT2 Antibody Positve Control-protein if for use in research applications.
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: SLC1A2
Gene ID: 6506
Uniprot ID: EAA2_HUMAN
Post Translational Modifications Glycosylated. Palmitoylation at Cys-38 is not required for correct subcellular localization, but is important for glutamate uptake activity.
Function Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport.this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate.
Protein Name Excitatory Amino Acid Transporter 2
Glutamate/Aspartate Transporter Ii
Sodium-Dependent Glutamate/Aspartate Transporter 2
Solute Carrier Family 1 Member 2
Database Links Reactome: R-HSA-210455
Reactome: R-HSA-210500
Reactome: R-HSA-425393
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Excitatory Amino Acid Transporter 2 antibody
Anti-Glutamate/Aspartate Transporter Ii antibody
Anti-Sodium-Dependent Glutamate/Aspartate Transporter 2 antibody
Anti-Solute Carrier Family 1 Member 2 antibody
Anti-SLC1A2 antibody
Anti-EAAT2 antibody
Anti-GLT1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance