Trial size EIF4EBP1 antibodies available in the Antibody Validation Project
- What is EIF4EBP1
- Where is EIF4EBP1 found?
- What role does EIF4EBP1 play in disease?
- EIF4EBP1 antibodies in the Antibody Validation Project
- Customer reviewed EIF4EBP1 antibodies
- Other EIF4EBP1 antibodies available in the Antibody Validation Project
- Popular EIF4EBP1 antibodies not currently in the Antibody Validation Project
- How does the Antibody Validation Project work?
What is EIF4EBP1?
The Eukaryotic translation initiation factor 4E-binding protein 1 represses the initiation of translation that serves to regulate the activity of EIF4E by blocking its assembly into the eIF4F complex. It also mediates protein regulation via hormones, growth factors, cell stress and others, which signal using the mTORC1, Insulin signalling and MAP kinase pathways.
Where is EIF4EBP1 found?
EIF4EBP1 is present both in the nucleus and the cytoplasm, and is located within the 8p11- p12 genomic locus. In normal tissue, it is expressed in the gastrointestinal tract, pancreas, salivary gland and non-keratinized squamous epithelia. Under physiological stress, the hypophosphorylated protein located in the latter compartment can isolate eIF4E.
What role does EIF4EBP1 play in disease?
Over-expression is typically in a many human cancers, especially in breast cancer. Studies have proven that EIF4EBP1 plays a significant role in carcinogenesis.
EIF4EBP1 antibodies in the Antibody Validation Project
St John's Laboratory offers a variety of trial size primary antibodies which target EIF4EBP1, which are available to try through the Antibody Validation Project. Below we highlight those which have already been reviewed, as well as others which are available to try.
Customer reviewed EIF4EBP1 antibodies
|STJ90778||Anti-Phospho-4E-BP1 (S65) antibody||Rabbit||Polyclonal||4||IHC|
Other EIF4EBP1 antibodies available in the Antibody Validation Project
|STJ90162||Anti-Phospho-4E-BP1 (T46) antibody||Rabbit||Polyclonal||WB,IHC,ELISA|
|STJ90163||Anti-Phospho-4E-BP1 (T69) antibody||Rabbit||Polyclonal||WB,IHC,ELISA|
|STJ91237||Anti-Phospho-4E-BP1 (T70) antibody||Rabbit||Polyclonal||IHC,ELISA|
Popular EIF4EBP1 antibodies not currently in the Antibody Validation Project
How does the Antibody Validation Project work?
In order to help our customers with their choice of antibody with low risk, we offer one of the largest ranges of primary antibodies with trial size options available.
The Antibody Validation Project works like this.
1. Order your trial size antibody online.
2. Explore its suitability.
3. Return your results by posting them on the product page.
4. Receive a sample refund.
Find out more here.