| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZNF768 |
| Gene ID: | 79724 |
| Uniprot ID: | ZN768_HUMAN |
| Immunogen Region: | 140-270 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 140-270 of human ZNF768 (NP_078947.3). |
| Immunogen Sequence: | PGYESESSRYESQNTELKTQ SPEFEAQSSKFQEGAEMLLN PEEKSPLNISVGVHPLDSFT QGFGEQPTGDLPIGPPFEMP TGALLSTPQFEMLQNPLGLT GALRGPGRRGGRARGGQGPR PNICGICGKSF |
| Post Translational Modifications | May be phosphorylated at residue 'Ser-5' of the tandem heptapeptide repeats in the N-terminus. Phosphorylation might be increased upon RAS pathway activation and negatively regulate protein stability. |
| Function | Binds to mammalian-wide interspersed repeat (MIRs) sequences in euchromatin and promoter regions of genes at the consensus sequence 5'-GCTGTGTG-N20-CCTCTCTG-3', consisting of two anchor regions connected by a linker region.the linker region probably does not contribute to the binding specificity. Required for cell homeostasis. May be involved in transcriptional regulation (Probable). |
| Protein Name | Zinc Finger Protein 768 |
| Cellular Localisation | NucleusChromosomeLocalizes To Euchromatin |
| Alternative Antibody Names | Anti-Zinc Finger Protein 768 antibodyAnti-ZNF768 antibody |
Information sourced from Uniprot.org