| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-WDR36 (702-951) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
WDR36 |
| Gene ID: |
134430 |
| Uniprot ID: |
WDR36_HUMAN |
| Immunogen Region: |
702-951 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 702-951 of human WDR36 (NP_644810.1). |
| Immunogen Sequence: |
LRPLPADYVPSIVMLPGTCQ TQDVEVSEETVEPSDELIEY DSPEQLNEQLVTLSLLPESR WKNLLNLDVIKKKNKPKEPP KVPKSAPFFIPTIPGLVPRY AAPEQNNDPQQSKVVNLGVL AQKSDFCLKLEEGLVNNKYD TALNLLKESGPSGIETELRS LSPDCGGSIEVMQSFLKMIG MMLDRKRDFELAQAYLALFL KLHLKMLPSEPVLLEEITNL SSQVEENWTHLQSLFNQSM |
| Tissue Specificity | Expressed in heart, placenta, liver, skeletal muscle, kidney and pancreas. In ocular tissues, strong expression in iris, sclera, ciliary muscle, ciliary body, retina and optic nerve. |
| Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in the nucleolar processing of SSU 18S rRNA. Involved in T-cell activation and highly coregulated with IL2. |
| Protein Name | Wd Repeat-Containing Protein 36T-Cell Activation Wd Repeat-Containing ProteinTa-Wdrp |
| Database Links | Reactome: R-HSA-6790901Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Wd Repeat-Containing Protein 36 antibodyAnti-T-Cell Activation Wd Repeat-Containing Protein antibodyAnti-Ta-Wdrp antibodyAnti-WDR36 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
