| Function | Mediates the transfer of lipids between membranes at organelle contact sites. Binds phosphatidylinositol 3-phosphate. Functions as a tethering factor in the slow endocytic recycling pathway, to assist traffic between early and recycling endosomes. Involved in the transport of proacrosomal vesicles to the nuclear dense lamina (NDL) during spermatid development. Plays a role in the assembly of the Golgi apparatus, possibly by mediating trafficking to the Golgi membrane. Plays a role in the development of the nervous system, and may be required for neuron projection development. May also play a role during adipose tissue development. Required for maintenance of the ocular lens. |
| Protein Name | Intermembrane Lipid Transfer Protein Vps13bCohen Syndrome Protein 1Vacuolar Protein Sorting-Associated Protein 13b |
| Cellular Localisation | Recycling Endosome MembranePeripheral Membrane ProteinCytoplasmic VesicleSecretory VesicleAcrosome MembraneGolgi ApparatusCis-Golgi Network MembraneEndoplasmic Reticulum-Golgi Intermediate Compartment MembraneTrans-Golgi Network MembraneEarly Endosome MembraneLysosome MembraneLocalizes To Proacrosomal And Acrosomal Vesicles And Not The Golgi Apparatus During Acrosome Formation |
| Alternative Antibody Names | Anti-Intermembrane Lipid Transfer Protein Vps13b antibodyAnti-Cohen Syndrome Protein 1 antibodyAnti-Vacuolar Protein Sorting-Associated Protein 13b antibodyAnti-VPS13B antibodyAnti-CHS1 antibodyAnti-COH1 antibodyAnti-KIAA0532 antibody |
Information sourced from Uniprot.org
