| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | VEGFB |
| Gene ID: | 7423 |
| Uniprot ID: | VEGFB_HUMAN |
| Immunogen Region: | 30-207 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-121 of human VEGFB (NP_003368.1). |
| Immunogen Sequence: | GHQRKVVSWIDVYTRATCQP REVVVPLTVELMGTVAKQLV PSCVTVQRCGGCCPDDGLEC VPTGQHQVRMQILMIRYPSS QLGEMSLEEHSQ |
| Tissue Specificity | Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas. |
| Post Translational Modifications | VEGF-B186 is O-glycosylated. |
| Function | Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. |
| Protein Name | Vascular Endothelial Growth Factor BVegf-BVegf-Related FactorVrf |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-194313Reactome: R-HSA-195399 |
| Cellular Localisation | SecretedSecreted But Remains Associated To Cells Or To The Extracellular Matrix Unless Released By Heparin |
| Alternative Antibody Names | Anti-Vascular Endothelial Growth Factor B antibodyAnti-Vegf-B antibodyAnti-Vegf-Related Factor antibodyAnti-Vrf antibodyAnti-VEGFB antibodyAnti-VRF antibody |
Information sourced from Uniprot.org