| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | VAMP5 |
| Gene ID: | 10791 |
| Uniprot ID: | VAMP5_HUMAN |
| Immunogen Region: | 1-116 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-116 of human VAMP5 (NP_006625.1). |
| Immunogen Sequence: | MAGIELERCQQQANEVTEIM RNNFGKVLERGVKLAELQQR SDQLLDMSSTFNKTTQNLAQ KKCWENIRYRICVGLVVVGV LLIILIVLLVVFLPQSSDSS SAPRTQDAGIASGPGN |
| Post Translational Modifications | (Microbial infection) Targeted and hydrolyzed by C.botulinum neurotoxin type X (BoNT/X) which hydrolyzes the 40-Arg-|-Ser-41 bond and probably inhibits neurotransmitter release. It remains unknown whether BoNT/X is ever produced, or what organisms it targets. |
| Function | May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or GLUT4 trafficking. |
| Protein Name | Vesicle-Associated Membrane Protein 5 Vamp-5 Myobrevin |
| Cellular Localisation | Cell Membrane Single-Pass Type Iv Membrane Protein Endomembrane System Golgi Apparatus Trans-Golgi Network Membrane Associated With The Plasma Membrane As Well As Intracellular Perinuclear And Peripheral Vesicular Structures Of Myotubes Associated With The Trans-Golgi But Not With The Cis-Golgi Apparatus |
| Alternative Antibody Names | Anti-Vesicle-Associated Membrane Protein 5 antibody Anti-Vamp-5 antibody Anti-Myobrevin antibody Anti-VAMP5 antibody Anti-HSPC191 antibody |
Information sourced from Uniprot.org