| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UFC1 |
| Gene ID: | 51506 |
| Uniprot ID: | UFC1_HUMAN |
| Immunogen Region: | 1-167 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human UFC1 (NP_057490.2). |
| Immunogen Sequence: | MADEATRRVVSEIPVLKTNA GPRDRELWVQRLKEEYQSLI RYVENNKNADNDWFRLESNK EGTRWFGKCWYIHDLLKYEF DIEFDIPITYPTTAPEIAVP ELDGKTAKMYRGGKICLTDH FKPLWARNVPKFGLAHLMAL GLGPWLAVEIPDLIQKGVIQ HKEKCNQ |
| Post Translational Modifications | Ufmylated at Lys-122. Deufmylated by UFSP1. |
| Function | E2-like enzyme which specifically catalyzes the second step in ufmylation. Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage. Ufmylation is involved in various processes, such as ribosome recycling, response to DNA damage, interferon response or reticulophagy (also called ER-phagy). |
| Protein Name | Ubiquitin-Fold Modifier-Conjugating Enzyme 1Ufm1-Conjugating Enzyme 1 |
| Alternative Antibody Names | Anti-Ubiquitin-Fold Modifier-Conjugating Enzyme 1 antibodyAnti-Ufm1-Conjugating Enzyme 1 antibodyAnti-UFC1 antibodyAnti-CGI-126 antibodyAnti-HSPC155 antibody |
Information sourced from Uniprot.org