Anti-TWIST2 antibody (STJA0007015)

SKU:
STJA0007015
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Twist-related protein 2 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TWIST2
Gene ID: 117581
Uniprot ID: TWST2_HUMAN
Specificity: This antibody detects endogenous levels of TWIST2 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human TWIST2
Function Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of pro-inflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
Protein Name Twist-Related Protein 2
Class A Basic Helix-Loop-Helix Protein 39
Bhlha39
Dermis-Expressed Protein 1
Dermo-1
Database Links Reactome: R-HSA-8878166
Cellular Localisation Nucleus
Cytoplasm
Mainly Nuclear During Embryonic Development
Cytoplasmic In Adult Tissues
Alternative Antibody Names Anti-Twist-Related Protein 2 antibody
Anti-Class A Basic Helix-Loop-Helix Protein 39 antibody
Anti-Bhlha39 antibody
Anti-Dermis-Expressed Protein 1 antibody
Anti-Dermo-1 antibody
Anti-TWIST2 antibody
Anti-BHLHA39 antibody
Anti-DERMO1 antibody

Information sourced from Uniprot.org

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