| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TUB (130-230) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TUB |
| Gene ID: |
7275 |
| Uniprot ID: |
TUB_HUMAN |
| Immunogen Region: |
130-230 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 130-230 of human TUB (NP_003311.2). |
| Immunogen Sequence: |
LSSSGSTSYQVQEADSLASV QLGATRPTAPASAKRTKAAA TAGGQGGAARKEKKGKHKGT SGPAALAEDKSEAQGPVQIL TVGQSDHAQDAGETAAGGGE R |
| Function | Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate. Can bind DNA (in vitro). May contribute to the regulation of transcription in the nucleus. Could be involved in the hypothalamic regulation of body weight. Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages. |
| Protein Name | Tubby Protein Homolog |
| Cellular Localisation | CytoplasmNucleusSecretedCell MembranePeripheral Membrane ProteinCytoplasmic SideBinds Phospholipid And Is Anchored To The Plasma Membrane Through Binding Phosphatidylinositol 45-BisphosphateIs Released Upon Activation Of Phospholipase CTranslocates From The Plasma Membrane To The Nucleus Upon Activation Of Guanine Nucleotide-Binding Protein G(Q) Subunit AlphaDoes Not Have A Cleavable Signal Peptide And Is Secreted By A Non-Conventional Pathway |
| Alternative Antibody Names | Anti-Tubby Protein Homolog antibodyAnti-TUB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
