| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Proton-transporting V-type ATPase complex assembly regulator TMEM9 (29-79 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TMEM9 |
| Gene ID: |
252839 |
| Uniprot ID: |
TMEM9_HUMAN |
| Immunogen Region: |
29-79 aa |
| Specificity: |
This antibody detects endogenous levels of human TMEM9 |
| Immunogen: |
Synthesized peptide derived from the human TMEM9 at the amino acid range 29-79 |
| Post Translational Modifications | N-glycosylated. |
| Function | Transmembrane protein that binds to and facilitates the assembly of lysosomal proton-transporting V-type ATPase (v-ATPase), resulting in enhanced lysosomal acidification and trafficking. By bringing the v-ATPase accessory protein ATP6AP2 and the v-ATPase subunit ATP6V0D1 together, allows v-ATPase complex formation and activation. TMEM9-controlled vesicular acidification induces hyperactivation of Wnt/beta-catenin signaling, involved in development, tissue homeostasis and tissue regeneration, through lysosomal degradation of adenomatous polyposis coli/APC. In the liver, involved in hepatic regeneration. |
| Protein Name | Proton-Transporting V-Type Atpase Complex Assembly Regulator Tmem9V-Atpase Assembly Regulator Tmem9Dermal Papilla-Derived Protein 4Transmembrane Protein 9Protein Tmem9 |
| Cellular Localisation | Lysosome MembraneSingle-Pass Type I Membrane ProteinLate Endosome MembraneEndosomeMultivesicular Body Membrane |
| Alternative Antibody Names | Anti-Proton-Transporting V-Type Atpase Complex Assembly Regulator Tmem9 antibodyAnti-V-Atpase Assembly Regulator Tmem9 antibodyAnti-Dermal Papilla-Derived Protein 4 antibodyAnti-Transmembrane Protein 9 antibodyAnti-Protein Tmem9 antibodyAnti-TMEM9 antibodyAnti-DERP4 antibodyAnti-TMEM9A antibodyAnti-HSPC186 antibodyAnti-PSEC0012 antibodyAnti-UNQ631 antibodyAnti-PRO1248 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
