| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Transmembrane protein 70, mitochondrial is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TMEM70 |
| Gene ID: | 54968 |
| Uniprot ID: | TMM70_HUMAN |
| Specificity: | This antibody detects endogenous levels of TMEM70 at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human TMEM70 |
| Function | Scaffold protein that participates in the c-ring assembly of mitochondrial ATP synthase (F(1)F(0) ATP synthase or complex V) by facilitating the membrane insertion and oligomer formation of the subunit c/ATP5MC1 through its interaction. Therefore, participates in the early stage of mitochondrial ATP synthase biogenesis and also protects subunit c/ATP5MC1 against intramitochondrial proteolysis. In addition, binds the mitochondrial proton-transporting ATP synthase complexes I and may play a role in the stability of its membrane-bound subassemblies. |
| Protein Name | Transmembrane Protein 70 - Mitochondrial |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane ProteinMostly Located Within The Inner Cristae Membrane |
| Alternative Antibody Names | Anti-Transmembrane Protein 70 - Mitochondrial antibodyAnti-TMEM70 antibody |
Information sourced from Uniprot.org