| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Transmembrane protein 119 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TMEM119 |
| Gene ID: | 338773 |
| Uniprot ID: | TM119_HUMAN |
| Specificity: | This antibody detects endogenous levels of TMEM119 at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human TMEM119 |
| Function | Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts. May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Up-regulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation. |
| Protein Name | Transmembrane Protein 119 Osteoblast Induction Factor Obif |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein Cytoplasm Endoplasmic Reticulum Membrane Secreted |
| Alternative Antibody Names | Anti-Transmembrane Protein 119 antibody Anti-Osteoblast Induction Factor antibody Anti-Obif antibody Anti-TMEM119 antibody Anti-PSEC0199 antibody Anti-UNQ731 antibody Anti-PRO1415 antibody |
Information sourced from Uniprot.org