| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TMBIM6 |
| Gene ID: | 7009 |
| Uniprot ID: | BI1_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TMBIM6 (NP_003208.2). |
| Immunogen Sequence: | MNIFDRKINFDALLKFSHIT PSTQQHLKKVYASFALCMFV AAAGAYVHMVTHFIQAGLLS ALGSLILMIWLMATPHSHET EQKRLGLLAGFAFLTGVGLG |
| Tissue Specificity | Highly abundant in testis. |
| Function | Suppressor of apoptosis. Modulates unfolded protein response signaling. Modulates ER calcium homeostasis by acting as a calcium-leak channel. Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation. |
| Protein Name | Bax Inhibitor 1Bi-1Testis-Enhanced Gene Transcript ProteinTransmembrane Bax Inhibitor Motif-Containing Protein 6 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Bax Inhibitor 1 antibodyAnti-Bi-1 antibodyAnti-Testis-Enhanced Gene Transcript Protein antibodyAnti-Transmembrane Bax Inhibitor Motif-Containing Protein 6 antibodyAnti-TMBIM6 antibodyAnti-BI1 antibodyAnti-TEGT antibody |
Information sourced from Uniprot.org