• Western blot analysis of extracts of various cell lines, using TLR10 antibody (STJ28415) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 50s.

Anti-TLR10 antibody (20-270) (STJ28415)

SKU:
STJ28415

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TLR10 (20-270) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TLR10
Gene ID: 81793
Uniprot ID: TLR10_HUMAN
Immunogen Region: 20-270
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-270 of human TLR10 (NP_001182036.1).
Immunogen Sequence: DAPELPEERELMTNCSNMSL RKVPADLTPATTTLDLSYNL LFQLQSSDFHSVSKLRVLIL CHNRIQQLDLKTFEFNKELR YLDLSNNRLKSVTWYLLAGL RYLDLSFNDFDTMPICEEAG NMSHLEILGLSGAKIQKSDF QKIAHLHLNTVFLGFRTLPH YEEGSLPILNTTKLHIVLPM DTNFWVLLRDGIKTSKILEM TNIDGKSQFVSYEMQRNLSL ENAKTSVLLLNKVDLLWDD
Tissue Specificity Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines.
Function Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Protein Name Toll-Like Receptor 10
Cd Antigen Cd290
Database Links Reactome: R-HSA-168142
Reactome: R-HSA-5603037
Reactome: R-HSA-975871
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Toll-Like Receptor 10 antibody
Anti-Cd Antigen Cd290 antibody
Anti-TLR10 antibody
Anti-UNQ315 antibody
Anti-PRO358 antibody

Information sourced from Uniprot.org

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