| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TCTN3 |
| Gene ID: | 26123 |
| Uniprot ID: | TECT3_HUMAN |
| Immunogen Region: | 200-475 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-475 of human TCTN3 (NP_056446.4). |
| Immunogen Sequence: | QTQSPPSFYRAGDPILTYFP KWSVISLLRQPAGVGAGGLC AESNPAGFLESKSTTCTRFF KNLASSCTLDSALNAASYYN FTVLKVPRSMTDPQNMEFQV PVILTSQANAPLLAGNTCQN VVSQVTYEIETNGTFGIQKV SVSLGQTNLTVEPGASLQQH FILRFRAFQQSTAASLTSPR SGNPGYIVGKPLLALTDDIS YSMTLLQSQGNGSCSVKRHE VQFGVNAISGCKLRLKKAD |
| Function | Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. May be involved in apoptosis regulation. Necessary for signal transduction through the sonic hedgehog (Shh) signaling pathway. |
| Protein Name | Tectonic-3 |
| Database Links | Reactome: R-HSA-5620912 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tectonic-3 antibodyAnti-TCTN3 antibodyAnti-C10orf61 antibodyAnti-TECT3 antibodyAnti-PSEC0041 antibodyAnti-UNQ1881 antibodyAnti-PRO4324 antibody |
Information sourced from Uniprot.org