| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TAF9 |
| Gene ID: | 6880 |
| Uniprot ID: | TAF9_HUMAN |
| Immunogen Region: | 1-172 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human TAF9 (NP_003178.1). |
| Immunogen Sequence: | MESGKTASPKSMPKDAQMMA QILKDMGITEYEPRVINQML EFAFRYVTTILDDAKIYSSH AKKATVDADDVRLAIQCRAD QSFTSPPPRDFLLDIARQRN QTPLPLIKPYSGPRLPPDRY CLTAPNYRLKSLQKKASTSA GRITVPRLSVGSVTSRPSTP TLGTPTPQTMSV |
| Function | The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. TAF9 is also a component of the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TAF9 and its paralog TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. Essential for cell viability. May have a role in gene regulation associated with apoptosis. |
| Protein Name | Transcription Initiation Factor Tfiid Subunit 9 Rna Polymerase Ii Tbp-Associated Factor Subunit G Staf31/32 Transcription Initiation Factor Tfiid 31 Kda Subunit Tafii-31 Tafii31 Transcription Initiation Factor Tfiid 32 Kda Subunit Tafii-32 Tafii32 |
| Database Links | Reactome: R-HSA-167161 Reactome: R-HSA-167162 Reactome: R-HSA-167172 Reactome: R-HSA-3214847 Reactome: R-HSA-674695 Reactome: R-HSA-6804756 Reactome: R-HSA-6807505 Reactome: R-HSA-73776 Reactome: R-HSA-73779 Reactome: R-HSA-75953 Reactome: R-HSA-76042 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Initiation Factor Tfiid Subunit 9 antibody Anti-Rna Polymerase Ii Tbp-Associated Factor Subunit G antibody Anti-Staf31/32 antibody Anti-Transcription Initiation Factor Tfiid 31 Kda Subunit antibody Anti-Tafii-31 antibody Anti-Tafii31 antibody Anti-Transcription Initiation Factor Tfiid 32 Kda Subunit antibody Anti-Tafii-32 antibody Anti-Tafii32 antibody Anti-TAF9 antibody Anti-TAF2G antibody Anti-TAFII31 antibody |
Information sourced from Uniprot.org