| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SYT5 |
| Gene ID: | 6861 |
| Uniprot ID: | SYT5_HUMAN |
| Immunogen Region: | 1-110 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human SYT5 (NP_003171.2). |
| Immunogen Sequence: | MFPEPPTPGPPSPDTPPDSS RISHGPVPPWALATIVLVSG LLIFSCCFCLYRKSCRRRTG KKSQAQAQVHLQEVKGLGQS YIDKVQPEVEELEPAPSGPG QQVADKHELG |
| Function | May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface. |
| Protein Name | Synaptotagmin-5Synaptotagmin VSytv |
| Database Links | Reactome: R-HSA-422356 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneSingle-Pass Membrane ProteinRecycling Endosome MembraneIn Mast CellsLocalizes To The Endocytic Recycling Compartment |
| Alternative Antibody Names | Anti-Synaptotagmin-5 antibodyAnti-Synaptotagmin V antibodyAnti-Sytv antibodyAnti-SYT5 antibody |
Information sourced from Uniprot.org