Host: | Mouse |
Applications: | IHC/IF |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-Synaptophysin is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
Clonality : | Monoclonal |
Clone ID : | SM5014 |
Conjugation: | Unconjugated |
Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Dilution Range: | IHC/IF (H) 1:200-1:500 |
Storage Instruction: | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
Gene Symbol: | SYP |
Gene ID: | 6855 |
Uniprot ID: | SYPH_HUMAN |
Immunogen: | Synthesized peptide derived from human Synaptophysin |
Post Translational Modifications | Ubiquitinated.mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. Phosphorylated by SRC. |
Function | Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity. |
Protein Name | SynaptophysinMajor Synaptic Vesicle Protein P38 |
Database Links | Reactome: R-HSA-9662360 |
Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneMulti-Pass Membrane ProteinSynapseSynaptosome |
Alternative Antibody Names | Anti-Synaptophysin antibodyAnti-Major Synaptic Vesicle Protein P38 antibodyAnti-SYP antibody |
Information sourced from Uniprot.org