| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Synaptogyrin 2/Cellugyrin (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 25-26kDa band observed in Human Muscle lysates (calculated MW of 24.8kDa according to NP_004701.1). Recommended concentration: 0.3-1µg/ml. Primary incubation was 1 hour. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SYNGR2 |
| Gene ID: | 9144 |
| Uniprot ID: | SNG2_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_004701.1; NP_001307452.1 |
| Specificity: | This antibody is expected to recognize both reported antibodies (NP_004701.1; NP_001307452.1). |
| Immunogen Sequence: | CIYGEGYSNAHESKQ |
| Post Translational Modifications | May be tyrosine phosphorylated by Src. |
| Function | May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane. (Microbial infection) May play a role in the assembly of cytoplasmic inclusion bodies required for SFTS phlebovirus replication. |
| Protein Name | Synaptogyrin-2Cellugyrin |
| Cellular Localisation | Cytoplasmic Vesicle MembraneMulti-Pass Membrane ProteinCytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneLocalizes To Cytoplasmic Vesicles Associated With The Recycling EndosomesLipid Droplet(Microbial Infection) Upon Sfts Phlebovirus InfectionThe Protein Localizes In Lipid Droplets And Inclusion Bodies |
| Alternative Antibody Names | Anti-Synaptogyrin-2 antibodyAnti-Cellugyrin antibodyAnti-SYNGR2 antibodyAnti-UNQ352 antibodyAnti-PRO615 antibody |
Information sourced from Uniprot.org