| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SULF2 |
| Gene ID: |
55959 |
| Uniprot ID: |
SULF2_HUMAN |
| Immunogen Region: |
726-870 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 726-870 of human SULF2 (NP_061325.1). |
| Immunogen Sequence: |
TCFTHDNQHWQTAPFWTLGP FCACTSANNNTYWCMRTINE THNFLFCEFATGFLEYFDLN TDPYQLMNAVNTLDRDVLNQ LHVQLMELRSCKGYKQCNPR TRNMDLGLKDGGSYEQYRQF QRRKWPEMKRPSSKSLGQLW EGWEG |
| Tissue Specificity | Expressed at highest levels in the ovary, skeletal muscle, stomach, brain, uterus, heart, kidney and placenta. |
| Post Translational Modifications | Processing by furin produces a secreted form. Glycosylation at Ser-583 negatively regulates its N-acetylglucosamine-6-sulfatase and arylsulfatase activities. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. |
| Function | Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. |
| Protein Name | Extracellular Sulfatase Sulf-2Hsulf-2ArylsulfataseN-Acetylglucosamine-6-Sulfatase Cleaved Into - Extracellular Sulfatase Sulf-2 Secreted Form |
| Cellular Localisation | Endoplasmic ReticulumGolgi ApparatusGolgi StackCell SurfaceExtracellular Sulfatase Sulf-2 Secreted Form: Secreted |
| Alternative Antibody Names | Anti-Extracellular Sulfatase Sulf-2 antibodyAnti-Hsulf-2 antibodyAnti-Arylsulfatase antibodyAnti-N-Acetylglucosamine-6-Sulfatase Cleaved Into - Extracellular Sulfatase Sulf-2 Secreted Form antibodyAnti-SULF2 antibodyAnti-KIAA1247 antibodyAnti-UNQ559 antibodyAnti-PRO1120 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
