• Western blot analysis of extracts of mouse brain, using SULF2 antibody (STJ111423) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-SULF2 antibody (726-870) (STJ111423)

SKU:
STJ111423

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SULF2 (726-870) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SULF2
Gene ID: 55959
Uniprot ID: SULF2_HUMAN
Immunogen Region: 726-870
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 726-870 of human SULF2 (NP_061325.1).
Immunogen Sequence: TCFTHDNQHWQTAPFWTLGP FCACTSANNNTYWCMRTINE THNFLFCEFATGFLEYFDLN TDPYQLMNAVNTLDRDVLNQ LHVQLMELRSCKGYKQCNPR TRNMDLGLKDGGSYEQYRQF QRRKWPEMKRPSSKSLGQLW EGWEG
Post Translational Modifications Processing by furin produces a secreted form. Glycosylation at Ser-583 negatively regulates its N-acetylglucosamine-6-sulfatase and arylsulfatase activities. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.
Function Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.
Protein Name Extracellular Sulfatase Sulf-2
Hsulf-2
Arylsulfatase
N-Acetylglucosamine-6-Sulfatase Cleaved Into - Extracellular Sulfatase Sulf-2 Secreted Form
Cellular Localisation Endoplasmic Reticulum
Golgi Apparatus
Golgi Stack
Cell Surface
Extracellular Sulfatase Sulf-2 Secreted Form: Secreted
Alternative Antibody Names Anti-Extracellular Sulfatase Sulf-2 antibody
Anti-Hsulf-2 antibody
Anti-Arylsulfatase antibody
Anti-N-Acetylglucosamine-6-Sulfatase Cleaved Into - Extracellular Sulfatase Sulf-2 Secreted Form antibody
Anti-SULF2 antibody
Anti-KIAA1247 antibody
Anti-UNQ559 antibody
Anti-PRO1120 antibody

Information sourced from Uniprot.org

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