| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-STOX1 (520-800) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
STOX1 |
| Gene ID: |
219736 |
| Uniprot ID: |
STOX1_HUMAN |
| Immunogen Region: |
520-800 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 520-800 of human STOX1 (NP_689922.3). |
| Immunogen Sequence: |
KPSQTGPKEKPFQKPRSLDS SRIFDGKAKEPYAEQPNDKM EAESIYINDPTVKPINDDFR GHLFSHPQQSMLQNDGKCCP FMESMLRYEVYGGENEVIPE VLRKSHSHFDKLGETKQTPH SLPSRGASFSDRTPSACRLV DNTIHQFQNLGLLDYPVGVN PLRQAARQDKDSEELLRKGF VQDAETTSLENEQLSNDDQA LYQNEVEDDDGACSSLYLEE DDISENDDLRQMLPGHSQY |
| Tissue Specificity | Expressed in placenta, including the invasive extravillus trophoblast cells. |
| Function | Involved in regulating the levels of reactive oxidative species and reactive nitrogen species and in mitochondrial homeostasis in the placenta. Required for regulation of inner ear epithelial cell proliferation via the AKT signaling pathway. Isoform A: Involved in cell cycle regulation by binding to the CCNB1 promoter, up-regulating its expression and promoting mitotic entry. Induces phosphorylation of MAPT/tau. |
| Protein Name | Storkhead-Box Protein 1Winged-Helix Domain-Containing Protein |
| Cellular Localisation | Isoform A: CytoplasmNucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeIn Epithelial CellsDiffusely Expressed In The CytoplasmParticularly In Peri-Membrane Cortical RegionsConcentrated At Centrosomes During MetaphaseIsoform B: NucleusIsoform C: NucleusNucleolus |
| Alternative Antibody Names | Anti-Storkhead-Box Protein 1 antibodyAnti-Winged-Helix Domain-Containing Protein antibodyAnti-STOX1 antibodyAnti-C10orf24 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
