| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STC1 |
| Gene ID: | 6781 |
| Uniprot ID: | STC1_HUMAN |
| Immunogen Region: | 18-247 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-247 of human STC1 (NP_003146.1). |
| Immunogen Sequence: | THEAEQNDSVSPRKSRVAAQ NSAEVVRCLNSALQVGCGAF ACLENSTCDTDGMYDICKSF LYSAAKFDTQGKAFVKESLK CIANGVTSKVFLAIRRCSTF QRMIAEVQEECYSKLNVCSI AKRNPEAITEVVQLPNHFSN RYYNRLVRSLLECDEDTVST IRDSLMEKIGPNMASLFHIL QTDHCAQTHPRADFNRRRTN EPQKLKVLLRNLRGEEDSPS HIKRTSHESA |
| Tissue Specificity | Expressed in most tissues, with the highest levels in ovary, prostate, heart, kidney and thyroid. In the kidney, expression is confined to the nephron, specifically in the distal convoluted tubule and in the collecting tubule. Not detected in the brain, liver, spleen, peripheral blood leukocytes and adrenal medulla. |
| Function | Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia. |
| Protein Name | Stanniocalcin-1Stc-1 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Stanniocalcin-1 antibodyAnti-Stc-1 antibodyAnti-STC1 antibodyAnti-STC antibody |
Information sourced from Uniprot.org