Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SPINK1 |
Gene ID: | 6690 |
Uniprot ID: | ISK1_HUMAN |
Immunogen Region: | 24-79 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-79 of human SPINK1 (NP_003113.2). |
Immunogen Sequence: | DSLGREAKCYNELNGCTKIY DPVCGTDGNTYPNECVLCFE NRKRQTSILIQKSGPC |
Function | Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens. In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production. |
Protein Name | Serine Protease Inhibitor Kazal-Type 1Pancreatic Secretory Trypsin InhibitorTumor-Associated Trypsin InhibitorTati |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Serine Protease Inhibitor Kazal-Type 1 antibodyAnti-Pancreatic Secretory Trypsin Inhibitor antibodyAnti-Tumor-Associated Trypsin Inhibitor antibodyAnti-Tati antibodyAnti-SPINK1 antibodyAnti-PSTI antibody |
Information sourced from Uniprot.org