| Post Translational Modifications | Phosphorylated by MAPK8 and MAPK14. |
| Function | The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Regulates lysosomal positioning by acting as an adapter protein which links PIP4P1-positive lysosomes to the dynein-dynactin complex. Assists PIKFYVE selective functionality in microtubule-based endosome-to-TGN trafficking. |
| Protein Name | C-Jun-Amino-Terminal Kinase-Interacting Protein 4Jip-4Jnk-Interacting Protein 4Cancer/Testis Antigen 89Ct89Human Lung Cancer Oncogene 6 ProteinHlc-6Jnk-Associated Leucine-Zipper ProteinJlpMitogen-Activated Protein Kinase 8-Interacting Protein 4Proliferation-Inducing Protein 6Protein Highly Expressed In TestisPhetSperm Surface ProteinSperm-Associated Antigen 9Sperm-Specific ProteinSunday Driver 1 |
| Database Links | Reactome: R-HSA-525793 |
| Cellular Localisation | CytoplasmPerinuclear RegionLysosome MembranePerinuclear Distribution In Response To Stress Signals Such As Uv RadiationIsoform 5: Cytoplasmic VesicleSecretory VesicleAcrosomeAssociated With The Plasma Membrane Of The Acrosomal Compartment And Also Localizes In The Acrosome Matrix |
| Alternative Antibody Names | Anti-C-Jun-Amino-Terminal Kinase-Interacting Protein 4 antibodyAnti-Jip-4 antibodyAnti-Jnk-Interacting Protein 4 antibodyAnti-Cancer/Testis Antigen 89 antibodyAnti-Ct89 antibodyAnti-Human Lung Cancer Oncogene 6 Protein antibodyAnti-Hlc-6 antibodyAnti-Jnk-Associated Leucine-Zipper Protein antibodyAnti-Jlp antibodyAnti-Mitogen-Activated Protein Kinase 8-Interacting Protein 4 antibodyAnti-Proliferation-Inducing Protein 6 antibodyAnti-Protein Highly Expressed In Testis antibodyAnti-Phet antibodyAnti-Sperm Surface Protein antibodyAnti-Sperm-Associated Antigen 9 antibodyAnti-Sperm-Specific Protein antibodyAnti-Sunday Driver 1 antibodyAnti-SPAG9 antibodyAnti-HSS antibodyAnti-KIAA0516 antibodyAnti-MAPK8IP4 antibodyAnti-SYD1 antibodyAnti-HLC6 antibody |
Information sourced from Uniprot.org
