| Tissue Specificity | Ubiquitously expressed, with high levels in testis. |
| Post Translational Modifications | DNA damage-regulated phosphorylation by kinases that may include ATM, ATR and PRKDC. |
| Function | ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks. |
| Protein Name | Swi/Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A-Like Protein 1Hepa-Related ProteinHharpSucrose Nonfermenting Protein 2-Like 1 |
| Cellular Localisation | NucleusRecruited To Damaged Dna Regions |
| Alternative Antibody Names | Anti-Swi/Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A-Like Protein 1 antibodyAnti-Hepa-Related Protein antibodyAnti-Hharp antibodyAnti-Sucrose Nonfermenting Protein 2-Like 1 antibodyAnti-SMARCAL1 antibodyAnti-HARP antibody |
Information sourced from Uniprot.org
