• Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-SLC43A2 antibody (122-172 aa) (STJ193627)

SKU:
STJ193627

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Large neutral amino acids transporter small subunit 4 (122-172 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC43A2
Gene ID: 124935
Uniprot ID: LAT4_HUMAN
Immunogen Region: 122-172 aa
Specificity: This antibody detects endogenous levels of LAT4 at Human/Mouse
Immunogen: Synthesized peptide derived from the human LAT4 at the amino acid range 122-172
Post Translational Modifications Glycosylated. Dephosphorylation at Ser-274 and phosphorylation at Ser-297 increase affinity and amino acid transport activity. Phosphorylation-dephosphorylation cycle is regulated by food-entrained diurnal rhythm and dietary proteins.
Function Uniporter that mediates the transport of the stereospecific L-phenylalanine, L-methionine and L-branched-chain amino acids, between the extracellular space and the cytoplasm and may control the transepithelial (re)absorption of neutral amino acid in kidney and small intestine. The transport activity is mediated through facilitated diffusion and is sodium ions-, chloride ions- and pH-independent.
Protein Name Large Neutral Amino Acids Transporter Small Subunit 4
L-Type Amino Acid Transporter 4
Solute Carrier Family 43 Member 2
Database Links Reactome: R-HSA-352230
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Basolateral Cell Membrane
Located At The Basolateral Membrane In The Small Intestine Enterocytes
Kidney Proximal Tubule
Thick Ascending Limb And
To A Minor Extent
Of Distal Convoluted Tubule Epithelial Cells
Alternative Antibody Names Anti-Large Neutral Amino Acids Transporter Small Subunit 4 antibody
Anti-L-Type Amino Acid Transporter 4 antibody
Anti-Solute Carrier Family 43 Member 2 antibody
Anti-SLC43A2 antibody
Anti-LAT4 antibody
Anti-PP7664 antibody

Information sourced from Uniprot.org

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