| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC26A4 |
| Gene ID: | 5172 |
| Uniprot ID: | S26A4_HUMAN |
| Immunogen Region: | 250-350 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human SLC26A4 (NP_000432.1). |
| Immunogen Sequence: | VLSIIYTLVEIFQNIGDTNL ADFTAGLLTIVVCMAVKELN DRFRHKIPVPIPIEVIVTII ATAISYGANLEKNYNAGIVK SIPRGFLPPELPPVSLFSEM L |
| Tissue Specificity | Highly expressed in the kidney (at protein level). High expression in adult thyroid, lower expression in adult and fetal kidney and fetal brain. Not expressed in other tissues. |
| Function | Sodium-independent transporter of chloride and iodide. Mediates electroneutral chloride-bicarbonate, chloride-iodide and chloride-formate exchange with 1:1 stoichiometry. Mediates electroneutral iodide-bicarbonate exchange. |
| Protein Name | PendrinSodium-Independent Chloride/Iodide TransporterSolute Carrier Family 26 Member 4 |
| Database Links | Reactome: R-HSA-427601Reactome: R-HSA-5619046 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
| Alternative Antibody Names | Anti-Pendrin antibodyAnti-Sodium-Independent Chloride/Iodide Transporter antibodyAnti-Solute Carrier Family 26 Member 4 antibodyAnti-SLC26A4 antibodyAnti-PDS antibody |
Information sourced from Uniprot.org