| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC25A14 (25-325) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC25A14 |
| Gene ID: |
9016 |
| Uniprot ID: |
UCP5_HUMAN |
| Immunogen Region: |
25-325 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 25-325 of human SLC25A14 (NP_001269124.1). |
| Immunogen Sequence: |
GHQKSTTVSHEMSGLNWKPF VYGGLASIVAEFGTFPVDLT KTRLQVQGQSIDARFKEIKY RGMFHALFRICKEEGVLALY SGIAPALLRQASYGTIKIGI YQSLKRLFVERLEDETLLIN MICGVVSGVISSTIANPTDV LKIRMQAQGSLFQGSMIGSF IDIYQQEGTRGLWRGV |
| Tissue Specificity | Mainly expressed in brain. Some expression in testis and pituitary. |
| Function | Transports inorganic anions (sulfate, sulfite, thiosulfate and phosphate) and, to a lesser extent, a variety of dicarboxylates (e.g. malonate, malate and citramalate) and, even more so, aspartate and glutamate and tricarboxylates. May catalyze the export of sulfite and thiosulfate (the hydrogen sulfide degradation products) from the mitochondria, thereby modulating the level of the hydrogen sulfide (Probable). Also can mediate a very low unidirectional transport of anions including sulfate, phosphate, (S)-malate, citrate, L-aspartate and L-glutamate. Maintains oxidative balance (through uncoupling activities) and ATP production (by modifying mitochondrial membrane potential). Is able to transport protons across lipid membranes. Also exhibits transmembrane chloride transport activity to a lesser extent. May modify mitochondrial respiratory efficiency and mitochondrial oxidant production. |
| Protein Name | Brain Mitochondrial Carrier Protein 1Bmcp-1Mitochondrial Uncoupling Protein 5Ucp 5Solute Carrier Family 25 Member 14 |
| Database Links | Reactome: R-HSA-167826Reactome: R-HSA-167827 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Brain Mitochondrial Carrier Protein 1 antibodyAnti-Bmcp-1 antibodyAnti-Mitochondrial Uncoupling Protein 5 antibodyAnti-Ucp 5 antibodyAnti-Solute Carrier Family 25 Member 14 antibodyAnti-SLC25A14 antibodyAnti-BMCP1 antibodyAnti-UCP5 antibodyAnti-UNQ791 antibodyAnti-PRO1682 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
