| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC10A2 (289-348) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC10A2 |
| Gene ID: |
6555 |
| Uniprot ID: |
NTCP2_HUMAN |
| Immunogen Region: |
289-348 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 289-348 of human SLC10A2 (NP_000443.1). |
| Immunogen Sequence: |
FPLIYSIFQLAFAAIFLGFY VAYKKCHGKNKAEIPESKEN GTEPESSFYKANGGFQPDEK |
| Tissue Specificity | Mainly expressed in ileum and kidney, lower expression in cecum. |
| Function | Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate. Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids (Probable). Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation. |
| Protein Name | Ileal Sodium/Bile Acid CotransporterApical Sodium-Dependent Bile Acid TransporterAsbtIleal Na(+/Bile Acid CotransporterIleal Sodium-Dependent Bile Acid TransporterIbatIsbtNa(+-Dependent Ileal Bile Acid TransporterSodium/Taurocholate Cotransporting Polypeptide - IlealSolute Carrier Family 10 Member 2 |
| Database Links | Reactome: R-HSA-159418 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Ileal Sodium/Bile Acid Cotransporter antibodyAnti-Apical Sodium-Dependent Bile Acid Transporter antibodyAnti-Asbt antibodyAnti-Ileal Na(+/Bile Acid Cotransporter antibodyAnti-Ileal Sodium-Dependent Bile Acid Transporter antibodyAnti-Ibat antibodyAnti-Isbt antibodyAnti-Na(+-Dependent Ileal Bile Acid Transporter antibodyAnti-Sodium/Taurocholate Cotransporting Polypeptide - Ileal antibodyAnti-Solute Carrier Family 10 Member 2 antibodyAnti-SLC10A2 antibodyAnti-ASBT antibodyAnti-ISBT antibodyAnti-NTCP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
