| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SFTPB |
| Gene ID: | 6439 |
| Uniprot ID: | PSPB_HUMAN |
| Immunogen Region: | 94-393 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 94-393 of human SFTPB (NP_000533.3). |
| Immunogen Sequence: | MAKEAIFQDTMRKFLEQECN VLPLKLLMPQCNQVLDDYFP LVIDYFQNQTDSNGICMHLG LCKSRQPEPEQEPGMSDPLP KPLRDPLPDPLLDKLVLPVL PGALQARPGPHTQDLSEQQF PIPLPYCWLCRALIKRIQAM IPKGALAVAVAQVCRVVPLV AGGICQCLAERYSVILLDTL LGRMLPQLVCRLVLRCSMDD SAGPRSPTGEWLPRDSECHL CMSVTTQAGNSSEQAIPQA |
| Function | Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. |
| Protein Name | Pulmonary Surfactant-Associated Protein BSp-B18 Kda Pulmonary-Surfactant Protein6 Kda ProteinPulmonary Surfactant-Associated Proteolipid Spl(Phe |
| Database Links | Reactome: R-HSA-5683826Reactome: R-HSA-5688031Reactome: R-HSA-5688849Reactome: R-HSA-5688890 |
| Cellular Localisation | SecretedExtracellular SpaceSurface Film |
| Alternative Antibody Names | Anti-Pulmonary Surfactant-Associated Protein B antibodyAnti-Sp-B antibodyAnti-18 Kda Pulmonary-Surfactant Protein antibodyAnti-6 Kda Protein antibodyAnti-Pulmonary Surfactant-Associated Proteolipid Spl(Phe antibodyAnti-SFTPB antibodyAnti-SFTP3 antibody |
Information sourced from Uniprot.org