• Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using Heparin Cofactor II Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of HepG2 cells, using Heparin Cofactor II Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-SERPIND1 antibody (41-90 aa) (STJ93474)

SKU:
STJ93474

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Heparin cofactor 2 (41-90 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SERPIND1
Gene ID: 3053
Uniprot ID: HEP2_HUMAN
Immunogen Region: 41-90 aa
Specificity: HC-II Polyclonal Antibody detects endogenous levels of HC-II protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Heparin Cofactor II at the amino acid range 41-90
Post Translational Modifications Phosphorylated by FAM20C in the extracellular medium.
Function Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.
Protein Name Heparin Cofactor 2
Heparin Cofactor Ii
Hc-Ii
Protease Inhibitor Leuserpin-2
Hls2
Serpin D1
Database Links Reactome: R-HSA-140837
Reactome: R-HSA-140875
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Alternative Antibody Names Anti-Heparin Cofactor 2 antibody
Anti-Heparin Cofactor Ii antibody
Anti-Hc-Ii antibody
Anti-Protease Inhibitor Leuserpin-2 antibody
Anti-Hls2 antibody
Anti-Serpin D1 antibody
Anti-SERPIND1 antibody
Anti-HCF2 antibody

Information sourced from Uniprot.org

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