| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:20-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SERPINA10 |
| Gene ID: | 51156 |
| Uniprot ID: | ZPI_HUMAN |
| Immunogen Region: | 165-444 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 165-444 of human SERPINA10 (NP_001094077.1). |
| Immunogen Sequence: | FAFIHKDFDVKETFFNLSKR YFDTECVPMNFRNASQAKRL MNHYINKETRGKIPKLFDEI NPETKLILVDYILFKGKWLT PFDPVFTEVDTFHLDKYKTI KVPMMYGAGKFASTFDKNFR CHVLKLPYQGNATMLVVLME KMGDHLALEDYLTTDLVETW LRNMKTRNMEVFFPKFKLDQ KYEMHELLRQMGIRRIFSPF ADLSELSATGRNLQVSRVLQ RTVIEVDERGTEAVAGILS |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. |
| Function | Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors. |
| Protein Name | Protein Z-Dependent Protease InhibitorPz-Dependent Protease InhibitorPziSerpin A10 |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Protein Z-Dependent Protease Inhibitor antibodyAnti-Pz-Dependent Protease Inhibitor antibodyAnti-Pzi antibodyAnti-Serpin A10 antibodyAnti-SERPINA10 antibodyAnti-ZPI antibodyAnti-UNQ707 antibodyAnti-PRO1358 antibody |
Information sourced from Uniprot.org