| Tissue Specificity | Expressed in all tissues tested with highest levels in pancreas, ovary, PBL, spleen and thymus.lowest levels in brain, placenta, lung and kidney. |
| Function | Involved in the functional recruitment of the Sin3-histone deacetylase complex (HDAC) to a specific subset of N-CoR corepressor complexes. Capable of transcription repression by N-CoR. Active in deacetylating core histone octamers (when in a complex) but inactive in deacetylating nucleosomal histones. (Microbial infection) Involved in transcriptional repression of HHV-1 genes TK and gC. |
| Protein Name | Histone Deacetylase Complex Subunit Sap3030 Kda Sin3-Associated PolypeptideSin3 Corepressor Complex Subunit Sap30Sin3-Associated Polypeptide P30 |
| Database Links | Reactome: R-HSA-3214815Reactome: R-HSA-427413Reactome: R-HSA-9679191 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Histone Deacetylase Complex Subunit Sap30 antibodyAnti-30 Kda Sin3-Associated Polypeptide antibodyAnti-Sin3 Corepressor Complex Subunit Sap30 antibodyAnti-Sin3-Associated Polypeptide P30 antibodyAnti-SAP30 antibody |
Information sourced from Uniprot.org
