| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SAP30 (C-Term) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SAP30 |
| Gene ID: |
8819 |
| Uniprot ID: |
SAP30_HUMAN |
| Immunogen Region: |
C-Term |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human SAP30 (NP_003855.1). |
| Immunogen Sequence: |
IELDKSARHLYICDYHKNLI QSVRNRRKRKGSDDDGGDSP VQDIDTPEVDLYQLQVNTLR RYKRHFKLPTRPGLNKAQLV EIVGCHFRSIPVNEKDTLTY FIYSVKNDKNKSDLKVDSGV H |
| Tissue Specificity | Expressed in all tissues tested with highest levels in pancreas, ovary, PBL, spleen and thymus.lowest levels in brain, placenta, lung and kidney. |
| Function | Involved in the functional recruitment of the Sin3-histone deacetylase complex (HDAC) to a specific subset of N-CoR corepressor complexes. Capable of transcription repression by N-CoR. Active in deacetylating core histone octamers (when in a complex) but inactive in deacetylating nucleosomal histones. (Microbial infection) Involved in transcriptional repression of HHV-1 genes TK and gC. |
| Protein Name | Histone Deacetylase Complex Subunit Sap3030 Kda Sin3-Associated PolypeptideSin3 Corepressor Complex Subunit Sap30Sin3-Associated Polypeptide P30 |
| Database Links | Reactome: R-HSA-3214815Reactome: R-HSA-427413Reactome: R-HSA-9679191 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Histone Deacetylase Complex Subunit Sap30 antibodyAnti-30 Kda Sin3-Associated Polypeptide antibodyAnti-Sin3 Corepressor Complex Subunit Sap30 antibodyAnti-Sin3-Associated Polypeptide P30 antibodyAnti-SAP30 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
