Western blot analysis of various lysates using S1PR4 Rabbit polyclonal antibody (STJ117311) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-S1PR4 antibody (C-Term) (STJ117311)

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STJ117311
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: S1PR4
Gene ID: 8698
Uniprot ID: S1PR4_HUMAN
Immunogen Region: C-Term
Specificity: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human S1PR4 (NP_003766.1).
Immunogen Sequence: SAVNPIIYSFRSREVCRAVL SFLCCGCLRLGMRGPGDCLA RAVEAHSGASTTDSSLRPRD SFRGSRSLSFRMREPLSSIS SVRSI
Tissue Specificity Specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level of expression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bone marrow, and appendix as well as in fetal liver, thymus, and lung.
Function Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.
Protein Name Sphingosine 1-Phosphate Receptor 4
S1p Receptor 4
S1p4
Endothelial Differentiation G-Protein Coupled Receptor 6
Sphingosine 1-Phosphate Receptor Edg-6
S1p Receptor Edg-6
Database Links Reactome: R-HSA-418594
Reactome: R-HSA-419408
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Sphingosine 1-Phosphate Receptor 4 antibody
Anti-S1p Receptor 4 antibody
Anti-S1p4 antibody
Anti-Endothelial Differentiation G-Protein Coupled Receptor 6 antibody
Anti-Sphingosine 1-Phosphate Receptor Edg-6 antibody
Anti-S1p Receptor Edg-6 antibody
Anti-S1PR4 antibody
Anti-EDG6 antibody

Information sourced from Uniprot.org

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