| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Replication termination factor 2 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RTF2 |
| Gene ID: | 51507 |
| Uniprot ID: | RTF2_HUMAN |
| Specificity: | This antibody detects endogenous levels of RTF2 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human RTF2 |
| Function | Replication termination factor which is a component of the elongating replisome (Probable). Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion (Probable). Interacts with nascent DNA. |
| Protein Name | Replication Termination Factor 2Rtf2Replication Termination Factor 2 Domain-Containing Protein 1 |
| Cellular Localisation | ChromosomeLocalizes At The Replication Fork |
| Alternative Antibody Names | Anti-Replication Termination Factor 2 antibodyAnti-Rtf2 antibodyAnti-Replication Termination Factor 2 Domain-Containing Protein 1 antibodyAnti-RTF2 antibodyAnti-C20orf43 antibodyAnti-RTFDC1 antibodyAnti-AD-007 antibodyAnti-CDA05 antibodyAnti-HSPC164 antibodyAnti-HSPC169 antibody |
Information sourced from Uniprot.org