| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-RSC1A1 (C-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | Rsc1a1 |
| Gene ID: | 69994 |
| Uniprot ID: | RSCA1_MOUSE |
| Immunogen Region: | C-Term |
| Specificity: | Specific for RSC1A1. |
| Immunogen: | A synthetic peptide from c-terminal region of mouse RSC1A1 conjugated to blue carrier protein was used as the antigen. |
| Function | Mediates transcriptional and post-transcriptional regulation of SLC5A1. Inhibits a dynamin and PKC-dependent exocytotic pathway of SLC5A1. Also involved in transcriptional regulation of SLC22A2. Exhibits glucose-dependent, short-term inhibition of SLC5A1 and SLC22A2 by inhibiting the release of vesicles from the trans-Golgi network. Regulates the expression of SLC5A1 in a tissue-specific manner and is specifically involved in its regulation in the small intestine. |
| Protein Name | Regulatory Solute Carrier Protein Family 1 Member 1Regulatory Subunit Of Sglt1Transporter Regulator Rs1Mrs1 |
| Cellular Localisation | Cell MembraneNucleusGolgi ApparatusTrans-Golgi NetworkLocalizes At The Inner Side Of The Plasma Membrane |
| Alternative Antibody Names | Anti-Regulatory Solute Carrier Protein Family 1 Member 1 antibodyAnti-Regulatory Subunit Of Sglt1 antibodyAnti-Transporter Regulator Rs1 antibodyAnti-Mrs1 antibodyAnti-Rsc1a1 antibody |
Information sourced from Uniprot.org