| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | RNF38 |
| Gene ID: | 152006 |
| Uniprot ID: | RNF38_HUMAN |
| Immunogen Region: | 10-90 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-90 of human RNF38 (NP_073618.3). |
| Immunogen Sequence: | NSASLPGHPNKVICERVRLQ SLFPLLPSDQNTTVQEDAHF KAFFQSEDSPSPKRQRLSHS VFDYTSASPAPSPPMRPWEM T |
| Tissue Specificity | Widely expressed with highest levels in testis. |
| Function | Acts as an E3 ubiquitin-protein ligase able to ubiquitinate p53/TP53 which promotes its relocalization to discrete foci associated with PML nuclear bodies. Exhibits preference for UBE2D2 as a E2 enzyme. |
| Protein Name | E3 Ubiquitin-Protein Ligase Rnf38Ring Finger Protein 38Ring-Type E3 Ubiquitin Transferase Rnf38 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Rnf38 antibodyAnti-Ring Finger Protein 38 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Rnf38 antibodyAnti-RNF38 antibody |
Information sourced from Uniprot.org