| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-RGS1/1R20 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 25kDa band seen in HepG2 lysate. Recommended for use at 0.5-2µg/ml.IHC: Paraffin embedded Human Thymus and Small Intestine. Recommended concentration: 2.5µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | RGS1 |
| Gene ID: | 5996 |
| Uniprot ID: | RGS1_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_002913.3 |
| Immunogen Sequence: | NLLNDLQANSLK |
| Function | Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors. Inhibits B cell chemotaxis toward CXCL12. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. |
| Protein Name | Regulator Of G-Protein Signaling 1Rgs1B-Cell Activation Protein Bl34Early Response Protein 1r20 |
| Database Links | Reactome: R-HSA-416476Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytosol |
| Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 1 antibodyAnti-Rgs1 antibodyAnti-B-Cell Activation Protein Bl34 antibodyAnti-Early Response Protein 1r20 antibodyAnti-RGS1 antibodyAnti-1R20 antibodyAnti-BL34 antibodyAnti-IER1 antibody |
Information sourced from Uniprot.org