| Host: |
Rabbit |
| Applications: |
IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RETN (19-108) is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IHC-P 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RETN |
| Gene ID: |
56729 |
| Uniprot ID: |
RETN_HUMAN |
| Immunogen Region: |
19-108 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 19-108 of human RETN (NP_001180303.1). |
| Immunogen Sequence: |
KTLCSMEEAINERIQEVAGS LIFRAISSIGLECQSVTSRG DLATCPRGFAVTGCTCGSAC GSWDVRAETTCHCQCAGMDW TGARCCRVQP |
| Tissue Specificity | Expressed in white adipose tissue (at protein level). Widely expressed, with particularly strong expression in lung, bone marrow, breast and peripheral blood. Expressed strongly in bone marrow and at lower levels in lung, but not detected in other tissues. Isoform 2 is detected in adipose tissue, bone marrow, brain, lung, peripheral blood, placenta and thymus. |
| Function | Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes. Promotes chemotaxis in myeloid cells. |
| Protein Name | ResistinAdipose Tissue-Specific Secretory FactorAdsfC/Ebp-Epsilon-Regulated Myeloid-Specific Secreted Cysteine-Rich ProteinCysteine-Rich Secreted Protein A12-Alpha-Like 2Cysteine-Rich Secreted Protein Fizz3 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-9615017 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Resistin antibodyAnti-Adipose Tissue-Specific Secretory Factor antibodyAnti-Adsf antibodyAnti-C/Ebp-Epsilon-Regulated Myeloid-Specific Secreted Cysteine-Rich Protein antibodyAnti-Cysteine-Rich Secreted Protein A12-Alpha-Like 2 antibodyAnti-Cysteine-Rich Secreted Protein Fizz3 antibodyAnti-RETN antibodyAnti-FIZZ3 antibodyAnti-HXCP1 antibodyAnti-RSTN antibodyAnti-UNQ407 antibodyAnti-PRO1199 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
