| Host: | Rabbit |
| Applications: | ELISA/IP/WB |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Relaxin 1 (100-150) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.5 µg/µl |
| Dilution Range: | WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:150 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Rxfp1 |
| Gene ID: | 295144 |
| Uniprot ID: | RXFP1_RAT |
| Immunogen Region: | 100-150 |
| Immunogen: | Synthetic peptide taken within amino acid region 100-150 on rat relaxin receptor 1 protein. |
| Tissue Specificity | Detected in brain cortex, and at low levels in testis. |
| Function | Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. |
| Protein Name | Relaxin Receptor 1 Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 7 Relaxin Family Peptide Receptor 1 |
| Database Links | Reactome: R-RNO-444821 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Relaxin Receptor 1 antibody Anti-Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 7 antibody Anti-Relaxin Family Peptide Receptor 1 antibody Anti-Rxfp1 antibody Anti-Lgr7 antibody |
Information sourced from Uniprot.org