| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RASSF6 (1-303) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RASSF6 |
| Gene ID: |
166824 |
| Uniprot ID: |
RASF6_HUMAN |
| Immunogen Region: |
1-303 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human RASSF6 (NP_001257320.1). |
| Immunogen Sequence: |
MTMMAHQYPSWIFINEKTFI TREQLNSLLKTYNIFYENQK NLHILYGETEDGKLIVEGML DIFWGVKRPIQLKIQDEKPF SSFTSMKSSDVFSSKGMTRW GEFDDLYRISELDRTQIPMS EKRNSQEDYLSYHSNTLKPH AKDEPDSPVLYRTMSEAALV RKRMKPLMMDRKERQKNRAS INGHFYNHEIENSPQDFALH IIFATGEQRRLKKTDIPLLQ RLLQGPSEKNARIFLMDKD |
| Tissue Specificity | Highest expression in thymus, kidney and placenta. Also detected in colon, small intestine and lung. Tends to be down-regulated in 30-60% of tumors derived from breast, colon, kidney liver, rectum, pancreas, stomach and the thyroid gland compared to the normal counterpart. |
| Function | Involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B. |
| Protein Name | Ras Association Domain-Containing Protein 6 |
| Alternative Antibody Names | Anti-Ras Association Domain-Containing Protein 6 antibodyAnti-RASSF6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
