| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RASD2 |
| Gene ID: | 23551 |
| Uniprot ID: | RHES_HUMAN |
| Immunogen Region: | 135-263 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 135-263 of human RASD2 (NP_055125.2). |
| Immunogen Sequence: | MVICGNKNDHGELCRQVPTT EAELLVSGDENCAYFEVSAK KNTNVDEMFYVLFSMAKLPH EMSPALHRKISVQYGDAFHP RPFCMRRVKEMDAYGMVSPF ARRPSVNSDLKYIKAKVLRE GQARERDKC |
| Tissue Specificity | Pancreatic endocrine cells (islets of Langerhans). |
| Post Translational Modifications | Farnesylated. Farnesylation is required for membrane targeting. |
| Function | GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination. |
| Protein Name | Gtp-Binding Protein RhesRas Homolog Enriched In StriatumTumor Endothelial Marker 2 |
| Cellular Localisation | Cell MembraneLipid-Anchor |
| Alternative Antibody Names | Anti-Gtp-Binding Protein Rhes antibodyAnti-Ras Homolog Enriched In Striatum antibodyAnti-Tumor Endothelial Marker 2 antibodyAnti-RASD2 antibodyAnti-TEM2 antibody |
Information sourced from Uniprot.org