| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RASD1 |
| Gene ID: | 51655 |
| Uniprot ID: | RASD1_HUMAN |
| Immunogen Region: | 132-281 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 132-281 of human RASD1 (NP_057168.1). |
| Immunogen Sequence: | TKENVDVPLVICGNKGDRDF YREVDQREIEQLVGDDPQRC AYFEISAKKNSSLDQMFRAL FAMAKLPSEMSPDLHRKVSV QYCDVLHKKALRNKKLLRAG SGGGGGDPGDAFGIVAPFAR RPSVHSDLMYIREKASAGSQ AKDKERCVIS |
| Tissue Specificity | Expressed in a variety of tissues including heart, cardiovascular tissues, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, gastrointestinal and reproductive tissues. |
| Post Translational Modifications | S-nitrosylation stimulates guanine-nucleotide exchange activity. |
| Function | Small GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65. |
| Protein Name | Dexamethasone-Induced Ras-Related Protein 1Activator Of G-Protein Signaling 1 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideCytoplasmPerinuclear RegionNucleus |
| Alternative Antibody Names | Anti-Dexamethasone-Induced Ras-Related Protein 1 antibodyAnti-Activator Of G-Protein Signaling 1 antibodyAnti-RASD1 antibodyAnti-AGS1 antibodyAnti-DEXRAS1 antibody |
Information sourced from Uniprot.org