Anti-RAB2B antibody (C-Term) (STJ140109)


Current Stock:
Host: Goat
Applications: WB
Reactivity: Human, Rat, Mouse, Monkey, Canine
Short Description: Goat polyclonal antibody anti-RAB2b, member RAS oncogene family (C-Term) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS, 20% Glycerol and 0.05% Sodium Azide.
Purification: This antibody is epitope-affinity purified from goat antiserum.
Concentration: 3 mg/ml
Dilution Range: WB 1:250-1:2000
Gene Symbol: RAB2B
Gene ID: 84932
Immunogen Region: C-Term
Accession Number: ENSG00000129472
Specificity: Detects levels of Rab2b protein in transfected cells with GFP-Rab2b by Western blot. This antibody is specific for Rab2b and it barely detects Rab2a.
Immunogen: Recombinant peptide derived from within residues 300 aa to the C-terminus of human ERp57 produced in E. coli.
Tissue Specificity Expressed in kidney, prostate, lung, liver, thymus, colon, pancreas, and skeletal muscle, and low levels in placenta. Not detected in heart, brain, spleen, testis, ovary, small intestine and leukocyte.
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between active GTP-bound and inactive GDP-bound states. In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology. Regulates the compacted morphology of the Golgi (Probable). Promotes cytosolic DNA-induced innate immune responses. Regulates IFN responses against DNA viruses by regulating the CGAS-STING signaling axis.
Protein Name Ras-Related Protein Rab-2b
Database Links Reactome: R-HSA-8873719
Cellular Localisation Cell Membrane
Cytoplasmic Side
Endoplasmic Reticulum Membrane
Golgi Apparatus Membrane
Cytoplasmic Vesicle
Secretory Vesicle
Localized In The Golgi Apparatus In The Round Spermatids And In The Acrosome In The Elongating Spermatid
Alternative Antibody Names Anti-Ras-Related Protein Rab-2b antibody
Anti-RAB2B antibody

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