![Anti-PTEN antibody [6H2.1] (STJ16101367)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/151876/346961/STJ16101367_1__87004.1681999192.jpg?c=1 "Anti-PTEN antibody [6H2.1] (STJ16101367)")
![Anti-PTEN antibody [6H2.1] (STJ16101367)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/151876/346961/STJ16101367_1__87004.1681999192.jpg?c=1 "Anti-PTEN antibody [6H2.1] (STJ16101367)")
| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-PTEN is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 6H2.1 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Formulation: | Tissue culture supernatant with sodium azide |
| Concentration: | Lot specific |
| Dilution Range: | IHC-P 1:50-1:100 |
| Storage Instruction: | Store at 2-8°C upon receipt. |
| Immunogen: | C-terminal 100 aa of PTEN |
| Background | PTEN gene is a tumor suppressor gene that maps to chromosome 10q23. PTEN, a novel tumor suppressor, functions as a regulator of both cell cycle progression and apoptosis ). Potentially, mutation and deletion of PTEN gene may result in a new signal transduction pathway related to human malignant tumors. Studies have demonstrated a reduction of PTEN expression in advanced breast cancers. Positive control tissue Breast, Renal Cell and Prostate carcinomas |
Information sourced from Uniprot.org