| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PROKR2 |
| Gene ID: | 128674 |
| Uniprot ID: | PKR2_HUMAN |
| Immunogen Region: | 1-60 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human PROKR2 (NP_658986.1). |
| Immunogen Sequence: | MAAQNGNTSFTPNFNPPQDH ASSLSFNFSYGDYDLPMDED EDMTKTRTFFAAKIVIGIAL |
| Tissue Specificity | Expressed in the ileocecum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary and brain. |
| Function | Receptor for prokineticin 2. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. |
| Protein Name | Prokineticin Receptor 2Pk-R2G-Protein Coupled Receptor 73-Like 1G-Protein Coupled Receptor I5eGpr73bGprg2 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Prokineticin Receptor 2 antibodyAnti-Pk-R2 antibodyAnti-G-Protein Coupled Receptor 73-Like 1 antibodyAnti-G-Protein Coupled Receptor I5e antibodyAnti-Gpr73b antibodyAnti-Gprg2 antibodyAnti-PROKR2 antibodyAnti-GPR73L1 antibodyAnti-PKR2 antibody |
Information sourced from Uniprot.org