| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | PRND |
| Gene ID: | 23627 |
| Uniprot ID: | PRND_HUMAN |
| Immunogen Region: | 20-160 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-160 of human PRND (NP_036541.2). |
| Immunogen Sequence: | HLSAVQTRGIKHRIKWNRKA LPSTAQITEAQVAENRPGAF IKQGRKLDIDFGAEGNRYYE ANYWQFPDGIHYNGCSEANV TKEAFVTGCINATQAANQGE FQKPDNKLHQQVLWRLVQEL CSLKHCEFWLERGAGLRVTM H |
| Tissue Specificity | Expressed in testis, in Sertoli cells, ejaculated spermatozoa and in seminal fluid (at protein level). |
| Post Translational Modifications | N-glycosylated. N-glycosylated at two distinct sites. O-glycosylated. |
| Function | Required for normal acrosome reaction and for normal male fertility. Can bind Cu(2+). |
| Protein Name | Prion-Like Protein DoppelPrplpPrion Protein 2 |
| Database Links | Reactome: R-HSA-163125 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Prion-Like Protein Doppel antibodyAnti-Prplp antibodyAnti-Prion Protein 2 antibodyAnti-PRND antibodyAnti-DPL antibodyAnti-UNQ1830 antibodyAnti-PRO3443 antibody |
Information sourced from Uniprot.org