• Western blot analysis of various lysates using PRG3 Rabbit polyclonal antibody (STJ118909) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-PRG3 antibody (18-225) (STJ118909)

SKU:
STJ118909

£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PRG3
Gene ID: 10394
Uniprot ID: PRG3_HUMAN
Immunogen Region: 18-225
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 18-225 of human PRG3 (NP_006084.2).
Immunogen Sequence: LHLENDAPHLESLETQADLG QDLDSSKEQERDLALTEEVI QAEGEEVKASACQDNFEDEE AMESDPAALDKDFQCPREED IVEVQGSPRCKICRYLLVRT PKTFAEAQNVCSRCYGGNLV SIHDFNFNYRIQCCTSTVNQ AQVWIGGNLRGWFLWKRFCW TDGSHWNFAYWSPGQPGNGQ GSCVALCTKGGYWRRAQCDK QLPFVCSF
Tissue Specificity Expressed in bone marrow. Not detected in placenta.
Function Possesses similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, stimulates neutrophil superoxide production and IL8 release, and histamine and leukotriene C4 release from basophils.
Protein Name Proteoglycan 3
Eosinophil Major Basic Protein Homolog
Prepro-Major Basic Protein Homolog
Prepro-Mbph
Database Links Reactome: R-HSA-6798695
Cellular Localisation Cytoplasmic Granule
Localized To The Eosinophil Secondary Granule
Alternative Antibody Names Anti-Proteoglycan 3 antibody
Anti-Eosinophil Major Basic Protein Homolog antibody
Anti-Prepro-Major Basic Protein Homolog antibody
Anti-Prepro-Mbph antibody
Anti-PRG3 antibody
Anti-MBPH antibody
Anti-UNQ486 antibody
Anti-PRO1002 antibody

Information sourced from Uniprot.org

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