Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | PRDM15 |
Gene ID: | 63977 |
Uniprot ID: | PRD15_HUMAN |
Immunogen Region: | 1268-1507 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1268-1507 of human PRDM15 (NP_071398.3). |
Immunogen Sequence: | IDASSIGIVQPELTLEQEDL AEGKHGKAAKRSHKRKQKPE EEAGAPVPEDATFSEYSEKE TEFTGSVGDETNSAVQSIQQ VVVTLGDPNVTTPSSSVGLT NITVTPITTAAATQFTNLQP VAVGHLTTPERQLQLDNSIL TVTFDTVSGSAMLHNRQNDV QIHPQPEASNPQSVAHFINL TTLVNSITPLGSQLSDQHPL TWRAVPQTDVLPPSQPQAPP QQAAQPQVQAEQQQQQMYS |
Tissue Specificity | Detected in all tissues examined. |
Function | Sequence-specific DNA-binding transcriptional regulator. Plays a role as a molecular node in a transcriptional network regulating embryonic development and cell fate decision. Stimulates the expression of upstream key transcriptional activators and repressors of the Wnt/beta-catenin and MAPK/ERK pathways, respectively, that are essential for naive pluripotency and self-renewal maintenance of embryonic stem cells (ESCs). Specifically promotes SPRY1 and RSPO1 transcription activation through recognition and direct binding of a specific DNA sequence in their promoter regions. Involved in early embryo development. Also plays a role in induced pluripotent stem cells (iPSCs) reprogramming. |
Protein Name | Pr Domain Zinc Finger Protein 15Pr Domain-Containing Protein 15Zinc Finger Protein 298 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Pr Domain Zinc Finger Protein 15 antibodyAnti-Pr Domain-Containing Protein 15 antibodyAnti-Zinc Finger Protein 298 antibodyAnti-PRDM15 antibodyAnti-C21orf83 antibodyAnti-ZNF298 antibody |
Information sourced from Uniprot.org